Drug class: Iron products. Before using, check this product visually for particles or discoloration. The cost of Venofer is $145 for a dose of 300 mg and Monoferric is $274 for a dose of 500mg. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or Anemia caused by the depletion of iron is called iron deficiency anemia. For all products, slow initial infusion is prudent; the patient is observed closely for infusion reactions. Venofer treatment may be repeated if necessary.
-Hgb deficit (grams) = Hgb deficit (g/dL) x blood volume (dL) -Iron deficit (mg) = Hgb deficit (grams) x 3.3 (mg Fe/g Hgb) [Note: 3.3 x 0.65 = 2.145] Sodium ferric gluconate (Ferrlecit) 62.5 mg . The dosing for iron replacement treatment in pediatric patients with Peritoneal or Hemodialysis-Dependent - CKD or Non-Dialysis Dependent CKD have not been established. Avoid or Use Alternate Drug. Maximum single dose of iron sucrose to be given at a time in Non-dialysis CKD patients is 500 mg but with limited experience. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy.
Iron Injection Administration | INJECTAFER HCP Use Caution/Monitor. There is limited experience with administration of an infusion of 500 mg of Venofer, diluted in a maximum of 250 mL of 0.9% NaCl, over a period of 3.5 to 4 hours on Day 1 and Day 14. OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. There is in depth information below the form on the method used and on the result provided. 1974 Jun;31(6):592-5. Medscape Education, Improving Quality of Care in Patients With Iron Deficiency Anemia and Inflammatory Bowel Disease, 2010feosol-carbonyl-fe-icar-c-carbonyl-iron-342171Drugs, encoded search term (iron sucrose (Venofer)) and iron sucrose (Venofer), Use of High-Dose Iron in Dialysis in US Tracks PIVOTAL Trial, FDA Watch List Adds Drugs With Anaphylaxis, Herpes, Fetal Death Risk, Dialysis Industry Mergers: Profits Rise as Patient Outcomes Worsen, Hematology-Oncology Guidelines: 2017 Midyear Review. On the other hand, slow decreases, such as that in chronic occult gastrointestinal bleeding are often difficult to diagnose. Use Caution/Monitor. Baloxavir may bind to polyvalent cations resulting in decreased absorption. Minor/Significance Unknown. Compare formulary status to other drugs in the same class.
calcium carbonate will decrease the level or effect of iron sucrose by increasing gastric pH. Schweiz Med Wochenschr; 100(7):301-3. Use Caution/Monitor. This site complies with the HONcode standard for trust- worthy health information: verify here. If dose exceeds 20mg/kg it should be rounded down to 20mg/kg OR administration of the total dose has to be split and given 7 days apart. Accessed: 4/12/2011. Estimates the iron deficit in preparation for iron replacement based on patient weight and haemoglobin. Minor/Significance Unknown.iron sucrose increases levels of calcium citrate by enhancing GI absorption. Minor/Significance Unknown. Intravenous iron sucrose: establishing a safe dose. informational and educational purposes only. This information is not individual medical advice and does not substitute for the advice of your health care professional. Either increases effects of the other by pharmacodynamic synergism. Applies only to oral form of both agents. The therapeutic management of IDA focuses on the replenishment of the iron stores through methods that have been mentioned above. 2.1 . Minor/Significance Unknown. Applies only to oral form of both agents.
PDF Treatment Guideline - Gloucestershire Royal Hospital Formula for calculating the required dose of iron sucrose Anemia. Applies only to oral form of both agents. Applies only to oral form of both agents. The elemental iron product used is Iron sucrose 20 mg/mL. Comparable efficacy to that of IV iron sucrose.
Monitor Closely (1)didanosine will decrease the level or effect of iron sucrose by increasing gastric pH. Applies only to oral form of both agents. Medically reviewed by Drugs.com. In key trials, ferric carboxymaltose increased Hb levels and replenished iron stores as effectively as IV iron sucrose . If these effects continue or worsen, tell your doctor.Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects.
One dose IV Iron replacement | Monoferric Aranesp (darbepoetin alfa) | Dosing Considerations Max Dose. iron sucrose decreases levels of minocycline by inhibition of GI absorption. Congenital Pulmonary Airway Malformation Volume Ratio (CVR) Calculator -. Most Each mL contains 20 mg of elemental iron. Either increases effects of the other by pharmacodynamic synergism. March 2, 2015 [IRON SUCROSE REQUIREMENT CALCULATION FOR SEVERE ANEMIA] DPMU Anantapuramu | National Health Mission 1 Formula for calculating the required dose of Iron sucrose 2.4 X Pre-pregnancy Weight in Kgs X Hb% deficit{11-actual Hb%} in mgs Plus Iron required to replenish the iron stores = 500mg Prepregnancy Weight = 45 kgs . Modify Therapy/Monitor Closely. iron sucrose decreases levels of methyldopa by inhibition of GI absorption. IV iron sucrose (Venofer) given as divided dosages, and low molecular weight iron dextran (CosmoFer) this can be given as divided dose or as a total dose infusion . Can't find what you need? Avoid or Use Alternate Drug. Intravenous iron-dextran: therapeutic and experimental possibilities [in German] Schweiz Med Wochenschr. There are physiological variation in iron reserves such as the decrease during menstruation period. 2010;18(3).
Clinical calculators for obstetrics and gynaecology - calculosaurus Ferrlecit has been administered at sequential dialysis sessions by infusion or by slow intravenous injection during the dialysis session itself.
Intravenous iron therapy for patients with anemia Inspect parenteral drug products visually for the absence of particulate matter and discoloration prior to administration. The dosage of Venofer is expressed in mg of elemental iron. J Lab Clin Med. 2010;18(3). Administer a test INFeD dose prior to the first therapeutic dose.
Venofer / Products / American Regent This site contains information for licensed healthcare professionals in the United States. IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. Individual plans may vary Intravenous iron-dextran: therapeutic and experimental possibilities. Use Caution/Monitor. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. Injection site discoloration has been reported following extravasation. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. Hanson DB, Hendeles L. Guide to total dose intravenous iron dextran therapy. Modify Therapy/Monitor Closely. Official Journal of the International Society of Nephrology. iron sucrose decreases levels of demeclocycline by inhibition of GI absorption. Use Caution/Monitor. 1995 Mar-Apr;11(2):163-8. If we don't have the calculator you need then tell us the details and we'll make it for you. ANNA J. Applies only to oral form of both agents. UpToDate. Schweiz Med Wochenschr. Applies only to oral form of both agents. Applies only to oral form of both agents. -Hgb deficit (grams) = Hgb deficit (g/dL) x blood volume (dL) -Iron deficit (mg) = Hgb deficit (grams) x 3.3 (mg Fe/g Hgb) [Note: 3.3 x 0.65 = 2.145] -Volume of parenteral iron product req'd (mL) = [Iron deficit (mg)] / C(mg/mL) Final calculations: -Hgb iron deficit (mg) = weight (kg) x (14 - Hgb) x (2.145) -Volume of product required (mL) = [weight (kg)x (14 - Hgb) x (2.145)] / C Where C= concentration of elemental iron (mg/ml) in the product being used: Iron dextran: 50 mg/mL.
PDF PRODUCT MONOGRAPH - pdf.hres.ca Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)- . 5. Avoid or Use Alternate Drug. Monitor Closely (1)omeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Applies only to oral form of both agents.
Iron Sucrose - Injection - Alberta Applies only to oral form of both agents. Venofer (Iron Sucrose Injection) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Intravenous therapy is usually recommended in case of contraindications to oral iron, comorbidities that prevent absorption, chronic renal impairment or iron replacement needs to be rapid. sodium citrate/citric acid will decrease the level or effect of iron sucrose by increasing gastric pH. Symptoms associated with Venofer total dosage or infusing too rapidly included hypotension, dyspnea, headache, vomiting, nausea, dizziness, joint aches, paresthesia, abdominal and muscle pain, edema and cardiovascular collapse.
Parenteral Iron Replacement For Anemia Calculator - MDApp Applies only to oral form of both agents. Applies only to oral form of both agents. Monitor Closely (1)nizatidine will decrease the level or effect of iron sucrose by increasing gastric pH. Then you can click on the Print button to open a PDF in a separate window with the inputs and results. Only administer Feraheme as an intravenous infusion over at least 15 minutes and only when personnel and therapies are immediately available for the treatment of anaphylaxis and other hypersensitivity reactions. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. By clicking send, you acknowledge that you have permission to email the recipient with this information. This information does not assure that this product is safe, effective, or appropriate for you. Most studies have used IV iron sucrose (maximum dose of 200 mg per setting) or ferric carboxymaltose (maximum dose of 1000 mg per week). Philadelphia, PA: Lippincott Williams & Wilkins;2013;303-307. Results: Twelve children (6 females) aged 1.2-14 years (median age 8.9 years) received at least one dose of . Iron metabolism needs to be balanced and bleeding, the major cause of iron deficiency (for instance in menstruation in females and chronic occult gastrointestinal bleeding) needs to be addressed. Minor (2)calcium acetate decreases levels of iron sucrose by inhibition of GI absorption. commonly, these are "non-preferred" brand drugs or specialty esomeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Iron sucrose (Venofer) 100 mg/5 mL vial 200 - 300 mg given every 3-7 days 300 mg doses are given over 90 minutes 500 mg/dose. Properly discard this product when it is expired or no longer needed. The recommended dosage of iron sucrose for repletion of iron deficiency in patients undergoing hemodialysis is 5ml of iron sucrose (100mg of elemental iron) delivered intravenously during the dialysis session. Copyright 2014 - 2023 The Calculator .CO |All Rights Reserved|Terms and Conditions of Use, Intravenous iron-dextran: therapeutic and experimental possibilities, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Treatment of iron deficiency anemia associated with gastrointestinal tract diseases, Diagnosis and management of iron deficiency anaemia: a clinical update. Transferrin saturation (TSAT) values increase rapidly after intravenous administration of iron sucrose; do not perform serum iron measurements for at least 48 hours after intravenous dosing. Mean Corpuscular Hemoglobin Concentration (MCHC) Calculator, Red Blood Cell (RBC) Indices Calculator, Iron Deficiency In Pregnancy Calculator. Each mL contains 20 mg of elemental . Koch TA, Myers J, Goodnough LT. Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations. Applies only to oral form of both agents. This drug is available at a middle level co-pay. Crown Rump Length and Nuchal Translucency. 1) Ganzoni AM. iron sucrose decreases levels of levothyroxine by inhibition of GI absorption. Applies only to oral form of both agents. The two formulas used are presented below: Iron deficit in mg = Weight in kg x (14 - Hb in g/dL) x 2.145 Volume of product required in mL = Iron deficit in mg / C in mg/mL Where C is the concentration of the iron product: 50 mg/mL for Iron dextran; 20 mg/mL for Iron sucrose; 5 mg/mL for Ferric gluconate. Intravenous (IV) iron products (use in adults) Dosing information in this table is for adults and includes some dosing recommendations not listed in the approved product information. Monitor Closely (1)vonoprazan will decrease the level or effect of iron sucrose by inhibition of GI absorption.
Treatment of iron deficiency anemia in adults - UpToDate Iron sucrose: 20 mg/mL. In most cases, adult patients require a cumulative dose of elemental iron of at least 1 g. Most commonly, iron replenishment therapy is done intravenously: As total dose (iron-dextran or iron carboxymaltose); Iron deficiency is common during childhood growth, prolonged periods of sickness, in convalescence or during pregnancy.